Endometriosis
A Chronic, Progressive Inflammatory Condition
Demanding Early Intervention
Approximately 10% of women globally are affected. Early diagnosis is critical — yet the average time to diagnosis remains 7 to 11 years.
A disease that affects every aspect of a woman's life
Endometriosis is a chronic, progressive inflammatory condition that, if left untreated, can lead to significant sequelae with a profound effect on the quality of life for millions of women worldwide. It is estimated that approximately 10% of women globally are affected by different aspects of this multifaceted inflammatory disease.
Unfortunately, endometriosis can begin at a very young age, as early as early adolescence, and its inflammatory residual effects may continue for decades, even after menopause, if it remains undiagnosed and untreated.
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Women affected globally
The Progressive and Destructive
Impact of Endometriosis
Given the inflammatory and progressive nature of endometriosis, early diagnosis and proper curative and preventative intervention are crucial to halt the ongoing insult to the woman's pelvic organs.
The progressive, inflammatory, and destructive effect of endometriosis directly involves the reproductive organs, causing long-standing effects on fertility, which presents a significant challenge for women battling infertility.
Furthermore, this destructive inflammatory process damages the complex autonomous network of pelvic nerves, leading to significant hyperexcitement and, consequently, pelvic nerve dysfunction (pelvic neuropathy). This complex cascade of events has significant consequences for a woman's quality of life by causing progressive pain and resulting in significant pelvic floor dysfunction affecting the functionality of vital pelvic organs.
Affected Pelvic Organs
Click to learn how each organ is affected
Lower Urinary Tract
Symptoms can include urinary urgency, frequency, difficulty emptying the bladder, multiple episodes of getting up at night to urinate (nocturia), and a phantom feeling of recurrent UTI that does not respond to antibiotic regimens.
Lower Gastrointestinal Tract
Reproductive Organs
Pelvic Floor Muscles
Critical Takeaway
The impact of this progressive, inflammatory, and neuropathy-driven effect of endometriosis significantly diminishes a patient's quality of life. It is critically important to break this vicious cycle as early as possible to prevent long-term damage to vital female organs.
“The delayed detection of endometriosis costs millions of women their quality of life and costs healthcare systems billions of dollars.”
Obstacles to
Early Diagnosis
Despite significant scientific progress, the early detection and diagnosis of endometriosis remain a challenge. The average time to diagnosis is estimated to be between 7 to 11 years, which is unacceptable.
“This current state emphasizes that the delayed detection of endometriosis costs millions of women their quality of life and costs healthcare systems billions of dollars to manage the often severe and irreversible damage.”
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Of women worldwide
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Average diagnosis delay
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Suffer fertility impact
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Of clinical research
The PelviQuest Project
Revolutionizing Endometriosis Management
It is critical to create a task force to find a solution for the endometriosis dilemma affecting over 10% of women. Current guidelines, some unchanged for over 50 years, require a significant update.
The Missing First Step
The key missing first step is early detection with acceptable precision and accuracy. A reliable diagnostic tool with high sensitivity and specificity is critically needed to change the entire game. The significant limitations of traditional imaging and blood tests mandate finding a different route.
20+ Years
Expert Endo Surgeon
Experience Meets Innovation
Dr. Shakiba, a leading endometriosis surgeon and specialist with over 20 years of experience managing complex endometriosis patients in the New York and New Jersey area, is taking significant steps to address this.
His extensive experience, surgical skill in minimally invasive excision of endometriosis using robotic and laparoscopic platforms, deep knowledge of pelvic nerve pathology, and strong background in research have led him to initiate the PelviQuest Project to solve the dilemma of early diagnosis.
Leveraging AI and Data for Early Diagnosis
Dr. Shakiba's focus is on creating a universal database of all patients presenting to his clinic, scientifically tracking all patient symptoms and physical exams and matching them with intraoperative findings during surgery.
Diagnose endometriosis simply based on standardized questionnaires and physical exams, constantly supported by research matching data with intraoperative findings.
Revolutionize the staging of endometriosis intraoperatively using AI technology.
The PelviQuest platform, which includes a dual app for patients and healthcare providers, combined with long-term AI technology, will provide significant insight for the early diagnosis of endometriosis.
Global Scale
Worldwide collaboration
Universal Standards, Global Impact
The PelviQuest Project is actively seeking to partner with expert-level endometriosis surgeons worldwide to enrich the database volume and ultimately improve the sensitivity and specificity of the predictive value of the collected data.
The ultimate goal of the PelviQuest app
Quick Access for Patients
Provide millions of patients worldwide with quick and easy access to answers regarding their pelvic health.
Universal Provider Approach
Offer a universal approach for gynecologists and other healthcare providers for the management of endometriosis, from the first patient visit to surgery.
Outcome Monitoring
Create an excellent outcome monitoring tool to manage patients' symptoms postoperatively.
Research Platform
Serve as a reliable, universal, and self-correctable tool for endometriosis research for years to come.
A New Window for Healthcare
This universal tool is hoped to solve the most critical dilemma — early diagnosis — and open a new window for the healthcare community to revise outdated guidelines and train a new generation of surgeons proficient in endometriosis surgery and, more importantly, pelvic nerve surgery.
Funded by Passion, Driven by Purpose
The PelviQuest Project is fully funded by Dr. Shakiba and is underway to revolutionize the quality of life of millions of women suffering from pelvic pain.
Investment opportunities for universal expansion are welcome.
Take the first step
toward answers
If you or someone you know is experiencing pelvic pain, don't dismiss it. The PelviQuest app can help you track, understand, and communicate your symptoms.